Surgical stress and cancer progression: the twisted tango
Surgical resection is an important avenue for cancer treatment, which, in most cases, can effectively alleviate the patient symptoms. However, accumulating evidence has documented that surgical resection potentially enhances metastatic seeding of tumor cells. In this review, we revisit the literature on surgical stress, and outline the mechanisms by which surgical stress, including ischemia/reperfusion injury, activation of sympathetic nervous system, inflammation, systemically hypercoagulable state, immune suppression and effects of anesthetic agents, promotes tumor metastasis. We also propose preventive strategies or resolution of tumor metastasis caused by surgical stress.
The effects of different drugs and schedule of their application
Healthcare, Free Full-Text
Healthcare, Free Full-Text
Surgical stress and cancer progression: the twisted tango
Surgical stress response and promotion of metastasis in colorectal
Stresses in the metastatic cascade: molecular mechanisms and
Effects of dexmedetomidine on A549 non-small cell lung cancer
The therapeutic and prognostic implications of immunobiology in
Frontiers The benefits of propofol on cancer treatment: Decipher
Immune-based therapies in penile cancer
Cancer Stem Cells are Actually Stem Cells with Disordered
Pharmaceuticals, Free Full-Text
Breast Sarcoma Case: ALT and LTP Flaps in the Management of
Cells, Free Full-Text