Yunlong Richard Cao on X: It's critical to test how these RBD hotspots could combine to achieve max immune evasion without losing affinity to ACE2. After careful consideration, besides the emerging K478R/F456L
Yunlong Richard Cao on X: Our paper on JN.1 is now online @TheLancetInfDis! The manuscript explains how a single RBD mutation L455S could turn BA.2.86 into a heavy immune evasive variant JN.1. Notably, JN.1 is now approaching worldwide
Yunlong Richard Cao (@yunlong_cao) / X
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Yunlong Cao Lab Peking University
Passive Immunotherapy Against SARS-CoV-2: From Plasma-Based Therapy to Single Potent Antibodies in the Race to Stay Ahead of the Variants
The Potential for SARS-CoV-2 to Evade Both Natural and Vaccine-induced Immunity
Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution