Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling

Chimeric antigen receptor engineered T cells and their application in the immunotherapy of solid tumours, Expert Reviews in Molecular Medicine

Epigenetic regulation of T cell exhaustion

Engineering genetic devices for in vivo control of therapeutic T cell activity triggered by the dietary molecule resveratrol

Transient “rest” induces functional reinvigoration and epigenetic remodeling in exhausted CAR-T cells

Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling

Evan W. Weber CHOP Research Institute

Frontiers CAR-T cell therapy for hematological malignancies: Limitations and optimization strategies

Immuno(T)herapy for age‐related diseases

Transient “rest” induces functional reinvigoration and epigenetic remodeling in exhausted CAR-T cells